Impact of the COVID-19 vaccination campaigns in Argentina during 2021: An observational quantification of the death probability for confirmed cases in Buenos Aires province.

Background: A SARS-CoV-2 (COVID-19) vaccination campaign was launched in Argentina in January 2021. The vaccines then available were administered to the population in several different schemes. This observational study presents a quantification of the impact of the different schemes on the probability of death for confirmed COVID-19 cases in Argentina's Buenos Aires Province. The results provide a local measure of the schemes' effectiveness that heretofore has been lacking. Methods: The study's main source of information is the Integrated Health Information System database, which contains 1,538,113 records of confirmed SARS-CoV-2 (COVID-19) cases reported in 2021 in the Province. To assess the real-world effectiveness of the vaccination campaign, two categorical variables representing vaccination status were defined. Probability of death was formulated as a generalized linear model with a logistic link and includes variables for geography, a socio-economic level index, symptom onset, sex, and vaccination status. The effectiveness level was derived from the death probability estimates. Findings: The study's findings indicated that the most effective vaccine was rAd26-rAd5 (Sputnik), with ChAdOx1-S (AZ/Covishield) and BBIBP-CorV (Sinopharm) following in efficacy, for both single and multiple doses. The effectiveness of a single dose was consistently below 50%, while it ranged from 50% to 90% for two or more doses. Notably, the analysis of variables such as the municipality of residence of the infected persons and the season of symptom onset yielded particularly intriguing insights. The socioeconomic level of a municipality emerged as a moderately strong predictor of the probability of death, which was marginally higher in municipalities with lower-income populations. Additionally, the data revealed an increased probability of death during the winter season. Interpretation: The vaccination campaigns carried out in Buenos Aires Province in 2021 significantly contributed to reducing the number of deaths due to SARS-CoV-2 (COVID-19) among its population. However, the extent of this impact varied considerably depending on individual characteristics such as age, health status, and vaccination schedule adherence.

Exposure to parks through the lens of urban mobility.

This work presents a portable framework to estimate potential park demand and park exposure through bipartite weighted networks. We use mobility information and open spatial information. Mobility information comes in the form of daily activities sampled from a model based on Call Detail Records (CDR). Spatial information comprise parks represented through OpenStreetMaps polygons and census tracts from the 2010 decennial US Census. The framework summarizes each city's information into one bipartite weighted network with the link weights representing the number of potential visits to a park from each census tract on an average weekday. We compare park exposure and park demand in Greater Los Angeles and Greater Boston in a pre-pandemic scenario. The park exposure of a census tract is calculated as the number of parks surrounding the daily activities of its inhabitants. The demand of a park is calculated as the number of daily activities surrounding it. We find that both cities' distribution of park exposure have similar shape with Boston having a higher average. On the other hand, the distribution of park demand is very similar in both cities, although their park spatial distributions are different. We include racial/ethnic information from the Census to explore how the park exposure connects tracts of different racial/ethnic groups. We associate parks to racial/ethnic groups based on the number of visitors from each group. Parks within minorities' tracts are mostly used by majority groups. Finally, through detecting communities in the network, we find that park exposure connects the cities locally, linking parks to their tracts nearby. Furthermore, we find a significant spatial correlation between network communities and different racial/ethnic composition in Los Angeles. This way, patterns of park exposure reproduce the separation among demographic groups of the city. Supplementary Information: The online version contains supplementary material available at 10.1140/epjds/s13688-022-00351-9.